Thrombophilia profile test
• Updated at: Aug 15, 2024 •
Thrombophilia Profile Test is one of the most important and sensitive tests, so it requires extreme precision and advanced modern laboratories.
What is the Thrombophilia?
- Thrombophilia occurs as a result of a problem in the blood formation process, which causes rapid blood clotting and the formation of clots
- Thrombophilia usually occurs as a result of genetic defects or as a result of exposure to a factor that contributes to increased blood clotting such as pregnancy.
Thrombophilia Profile Test at Bedaya Hospital
Bedaya Hospital provides two types of thrombophilia test, which are:
- Genetic testing: It helps identify genetic mutations that may cause blood clots.
- Functional testing: It helps measure the blood’s ability to form clots or break them.
- Thrombophilia Profile Test, includes:
- Complete blood count (CBC): it shows the number of red and white blood cells and platelets, which contributes to determining the risk of anemia or bleeding disorders.
- Partial thromboplastin time (PTT): to measure the effectiveness of clotting factors in the blood and can help diagnose blood clotting disorders such as antithrombin III deficiency.
- Prothrombin time (PT): to know the speed of blood clotting, and diagnose bleeding disorders such as hemophilia.
- Liver function tests (LFT): liver function is necessary for the production of clotting factors.
- Genetic test: to identify genetic mutations that increase the risk of blood clots.
Why Thrombophilia Profile Test is Performed?
Thrombophilia Test Results help in the following cases:
- find out if the person is infected with thrombophilia.
- Thrombophilia Profile Test can predict the risk of blood clots over the long term.
- Thrombophilia Profile Test helps to create a suitable treatment plan for each patient.
How Thrombophilia Profile Test is Performed?
Prothrombin Time (PT), which is one of the types of Thrombophilia Profile Test, is performed according to the following procedures:
- Taking a blood sample.
- In a designated laboratory bottle, the sample is mixed with sodium citrate.
- Using the separation device by placing the tube in it.
- The device will separate the clear liquid, “plasma,” from other blood cells.
- Exposing the plasma to a temperature similar to body temperature.
- Observing the sample.
- Measuring clotting time.
Thrombophilia Test Results
Thrombophilia test results must be discussed with the specialist doctor to confirm whether they carry serious indicators.
Normal thrombophilia test results depending on the type of Thrombophilia Profile Test performed.
According to international normalized ratio, the normal rate of blood clotting is between 0.8 - 1.1, while the normal clotting time ranges between 11 - 13.5 seconds.
How long do thrombophilia test results take?
Aadvanced health centers such as Bedaya Hospital provide a service to obtain thrombophilia test results on the same day of the test.
Thrombophilia Test Before Pregnancy
Doctors do not recommend performing thrombophilia test before pregnancy because:
- Hereditary blood clotting diseases are not common among women, as they affect a very small percentage of them.
- Testing and waiting for the results causes stress and anxiety, especially if the test shows unjustified positive results.
- There are few studies on the benefits of thrombophilia test before pregnancy.
Doctors advise women to undergo the test only in the following cases
- family history of blood clotting diseases.
- Rrecurrent miscarriage.
- Some medical conditions. (obesity, high blood pressure, gestational diabetes)
Thrombophilia Test in Pregnancy
Pregnant women undergo a routine Thrombophilia test as part of the regular examinations at the beginning of pregnancy, in order to determine the possibility of blood clots occurring during pregnancy and childbirth.
